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Polyethylene glycol (PEG 3350) is a water-soluble, inactive ingredient of which only a very small amount is absorbed in the gut or gastrointestinal tract, the rest moves through the body. It is known as an osmotic-type laxative. It helps constipation by holding more water in the bowel, making stool softer and easier to pass. Water is known as the universal solvent because more substances dissolve in water than in any other chemical. This has to do with the polarity of each water molecule. The hydrogen side of each water (H2O) molecule carries a slight positive electric charge, while the oxygen side carries a slight negative electric charge. Still because of their uses in day to day life it is thought better to study some more physical properties like ultrasonic velocity and hence adiabatic compressibility, free length, etc. Thus the present research work focuses on ultrasonics and related studies on these two mixtures. Ultrasound waves have been employed to enhance the delivery and activity of drugs for the past two decades. In the present work, an attempt has been made to compute the activation energy and hence to analyse the molecular interactions of aqueous solutions of Polyethylene Glycol (PEG 3350) at different concentrations (2%, 4%, 6%, 8% 10%, 12%, 14%, 16%, 18% and 20%) at different temperatures (303K, 308K, 313K, 318K) by determining relative viscosity, ultrasonic velocity and density. Various molecular interaction parameters like adiabatic compressibility, viscous relaxation time, inter molecular free length, free volume, internal pressure, etc are calculated at 303K. All these parameters have been discussed separately to throw light on the polymer - solvent interactions.
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